Peripartum Hysterectomy: 5 Year Review of Prevalence, Trend, Risk Factors and Obstetric Outcomes in a Tertiary Centre in Southern Nigeria

Kenneth Eghuan Okagua *

Department of Obstetrics and Gynaecology, Rivers State University Teaching Hospital, 6-8 Harley Street, Old GRA, Port Harcourt, Nigeria.

Felix Chikaike Clement Wekere

Department of Obstetrics and Gynaecology, Rivers State University Teaching Hospital, 6-8 Harley Street, Old GRA, Port Harcourt, Nigeria.

*Author to whom correspondence should be addressed.


Abstract

Peripartum hysterectomy is a life saving procedure performed during delivery or during the puerperium usually before discharge from delivery hospitalization. It is an indicator of near miss obstetrics and its obstetric outcomes can be used as an assessment of emergency obstetric care services. The aim of this study is a review of the risk factors, trends and obstetric outcomes of this procedure in a tertiary centre in Southern Nigeria.

The study was a 5 year retrospective study carried out at the Rivers State University Teaching hospital, Port Harcourt between January 2019 and December 2023. Majority, 54.2% of the participants were aged between 30 and 39 years (mean age of 33.7 ± 5.5) with 41.7% being Para 2. The mean gestational age was 37.3 ±2.8 and 70.8% had their pregnancies booked. Of the total of 8,739 deliveries, 4,956 were by Caesarean Sections (56.7%). A total of 24 peripartum hysterectomies were performed giving an incidence rate of 2.75 per 1000 deliveries. Sub-total hysterectomy was commonly performed (87.5%). 62.5% of the participants had a history of a previous caesarean section while 83.3% had a caesarean section in the index pregnancy. The indication for the procedure was uterine rupture and uterine atony in 85.7% of cases while the rest were for abnormal placentation. There was no maternal death and the perinatal mortality was 29.2%. All the participants required blood transfusion.   

The caesarean section rate of 56.7% in this study is high and is on the increase globally. Efforts to reduce the caesarean section rates is imperative as a history of caesarean section is a consistent risk factor for peripartum hysterectomy across various studies including this study. Obstetric haemorrhage from uterine rupture/atony requiring blood transfusion is the commonest indication and therefore the availability of blood transfusion services as an essential component of an emergency obstetric unit cannot be over-emphasized. The attendance of a senior obstetric staff improves outcomes.

Keywords: Peripartum hysterectomy, risk factors, obstetric outcomes


How to Cite

Okagua, Kenneth Eghuan, and Felix Chikaike Clement Wekere. 2024. “Peripartum Hysterectomy: 5 Year Review of Prevalence, Trend, Risk Factors and Obstetric Outcomes in a Tertiary Centre in Southern Nigeria”. Asian Research Journal of Gynaecology and Obstetrics 7 (1):124-34. https://journalarjgo.com/index.php/ARJGO/article/view/219.


References

Huque S, Roberts I, Fawole B, Chaudhri R, Arulkumaran S, Shakur-Still H. Risk factors for peripartum hysterectomy among women with postpartum haemorrhage: analysis of data from the WOMAN trial. BMC Pregnancy and Childbirth. 2018; 18:186

Obiechina N, Eleje GU, Ezebialu IU, Okeke C, Mbamara SU. Emergency peripartum hysterectomy in Nnewi, Nigeria: A 10-year review. Niger J Clin Pract. 2012;15:168-71.

Abasiattai AM, Umoiyoho AJ, Utuk NM, Inyang-Etoh EC, Asuquo OP. Emergency peripartum hysterectomy in a tertiary hospital in southern Nigeria. Pan African Medical Journal. 2013;15:60.

DOI:10.11604/pamj.2013.15.60.1879.

Dorigon A, Martins-Costa SH, Ramos JGL. Peripartum Hysterectomies over a Fifteen-year Period. Rev Bras Ginecol Obstet. 2021;43(1):3–8.

Campbell SM, Corcoran P, Manning E, Greene RA. Peripartum hysterectomy incidence, risk factors and clinical characteristics in Ireland. Eur J Obstet Gynecol Reprod Biol. 2016; 207:56– 61.

Khan B, Khan B, Sultana R, Bashir R, Deeba FA. Ten year review of emergency peripartum hysterectomy in a tertiary care hospital. J Ayub Med Coll Abbottabad. 2012;24(1):14–7.

Omole-Ohonsi A, Olayinka HT. Emergency peripartum hysterectomy in a developing country. J Obstet Gynaecol Can. 2012;34(10):954–60.

Whiteman MK, Kuklina E, Hillis SD, Jamieson DJ, Meikle SF, Posner SF, et al. Incidence and determinants of peripartum hysterectomy. Obstet Gynecol. 2006; 108(6):1486–92.

Bateman BT, Mhyre JM, Callaghan WM, Kuklina EV. Peripartum hysterectomy in the United States: nationwide 14 year experience. Am J Obstet Gynecol. 2012;206(1):63.e1–8.

Gbadebo AA, Edwin E, Anawo AC. Inevitable peripartum hysterectomy in a tropical Hospital: indications and maternofetal outcome. Pak j Med Sci. 2008;24:122126

van den Akker T, Brobbel C, Dekkers OM, Bloemenkamp KW. Prevalence, indications, risk indicators, and outcomes of emergency peripartum hysterectomy worldwide: a systematic review and meta-analysis. Obstet Gynecol. 2016;128(6):1281–94.

Nisar N, Sohoo NA. Emergency peripartum hysterectomy; frequency, indications and maternal outcome. J Ayub Med Coll Abbottabad. 2009;2:48-51

Oguejiofor CB, Eleje GU, Okafor OC, Okafor CG, Nkesi JC, James JE, Ezeigwe CO, Udochukwu OP, Okon VV. A Ten-year Review of Emergency Peripartum Hysterectomy in Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi. Journal of Gynecology Obstetrics and Mother Health. 2023;1(1):01-06.

Temizkan O, Angın D, Karakus R, Sanverdi I, Polat M, Karateke A. Changing trends in emergency peripartum hysterectomy in a tertiary obstetric center in Turkey during 2000–2013. J Turk Ger Gynecol Assoc. 2016;17:26-34

Okagua KE, Okagua J, Ogbondah B. Pregnancy Outcomes amongst booked parturients in a Semi-Urban Secondary Healthcare Setting in Southern Nigeria. International Journal of Clinical Obstetrics and Gynaecology 2024;8(1):33-36.

Pathiraja PDM, Jayawardane A. Evaluation of Peripartum Hysterectomy in a Tertiary Care Unit. Future Emerging Problem in Obstetric Practice? Journal of Women’s Health and Development. 2020;3(3):365-372.

Awoyesuku PA, Amadi SC, John DH, Kwosah NJ. Emergency Peripartum Hysterectomy: Frequency, Indications and Maternal Outcome at the Rivers State University Teaching Hospital, Port-Harcourt, Nigeria: A 5-Year Review”. EC Gynaecology. 2021;10(9):12-25.

Rabiu KA, Akinlusi FM, Adewunmi AA, Akinola OI. Emergency peripartum hysterectomy in a tertiary hospital in Lagos, Nigeria: a five-year review. Trop Doct 2010;40:1-4.

Umezurike CC, Feyi-Waboso PA, Adisa CA. Peripartum hysterectomy in Aba southeastern Nigeria. Aust N Z J Obstet Gynaecol 2008;48:580-2.

Ogunniyi SO, Esen UI. Obstetric Hysterectomy in Ile-Ife, Nigeria. Int J Gynaecol Obstet. 1990;32:23-7.

Rossi AC, Lee RH, Chmait RH. Emergency postpartum hysterectomy for uncontrolled postpartum bleeding: a systematic review. Obstet Gynecol. 2010;115(03):637–644.

Kalliandis AF, Rijntjes D, Brobbel C, Dekkers OM, Bloemenkamp KWM, van den Akker T. Incidence, Indications, Risk Factors and Outcomes of Emergency Peripartum Hysterectomy Worldwide: A Systematic Review and Meta-analysis. Obstet Gynecol. 2023;141(1):35–48.

Kalliandis AF, Maraschini A, Danis J, Colmorn LB, Deneux-Tharaux C, Donati S et al. Epidemiological analysis of peripartum hysterectomy across nine European countries. Acta Obstet Gynecol Scand. 2020;99(10):1364–1373.

de la Cruz CZ, Thompson EL, O’Rourke K, Nembhard WN. Cesarean section and the risk of emergency peripartum hysterectomy in high-income countries: a systemic review. Arch Gynecol Obstet. 2015;292:1201–1215.

Pettersen S, Falk RS, Vangen S, Nyflot LT. Peripartum hysterectomy due to severe postpartum hemorrhage: A hospital-based study. Acta Obstet Gynecol Scand. 2022; 101(7): 819 -826.

Yildirim GY, Koroglu N, Akca A, Talmac M, Dikmen S, Yildirim G et al. What is new in peripartum hysterectomy? A seventeen year review in a tertiary hospital. Taiwanese Journal of Obstetrics and Gynecology. 2021;60(1):95 -98.

Gica N, Ragea C, Botezatu R, Peltecu G, Gica C, Panaitescu AM. Incidence of Emergency Peripartum Hysterectomy in a Tertiary Obstetrics Unit in Romania. Medicina. 2022;58(1):111

Machado LS. Emergency peripartum hysterectomy: incidence, indications, risk factors and outcome. N Am J Med Sci. 2011;3(8):358 361.