Giant Uterine Fibroid: A Case Report of a Young Nulliparous Woman and Literature Review

Main Article Content

Michael Tyodoo Maanongun
Andrea Avershima Ornguze
Babarinde Ojo


Uterine leiomyoma, which arises from uterine smooth muscle, is the most common benign gynaecologic tumour of the female pelvis, however, giant fibroids are very rare in current practice, posing a management challenge. A 28-year-old nulliparous woman presented in a private clinic in Makurdi, Benue State, Nigeria with severe pain and slow growing abdominal mass with pressure symptoms due to a giant uterine fibroid. Intraoperatively, the mass was huge, weighed 11.6kg, was continuous with the uterus and tightly occupied the abdominal cavity with restricted mobility. Myomectomy was done after consideration of the patient’s wishes, fertility concerns and intra operative findings. Patient did well without complications and was discharged on day six.

Giant fibroid, uterus, leiomyoma, myomectomy

Article Details

How to Cite
Maanongun, M. T., Ornguze, A. A., & Ojo, B. (2021). Giant Uterine Fibroid: A Case Report of a Young Nulliparous Woman and Literature Review. Asian Research Journal of Gynaecology and Obstetrics, 5(2), 1-6. Retrieved from
Case Report


Ojabo AO, Adesiyun AG, Ifenne DI, Ameh N, Hembar-Hilekan S, Durosinlorun AM. Septic uterine myoma: A case report. Arch Int Surg. 2015;5(1):36-39.

Mason TC, Adair J, Lee YC. Postpartum pyomyoma. J Natl Med Assoc. 2005;97:826-8.

Fasubaa OB, Sowemimo OO, Ayegbusi OE, Abdur-Rahim ZF, Idowu BS, Ayobami O et al. Contributions of uterine fibroids to infertility at Ile-Ife, South Wester Nigeria. Trop J Obstet Gynaecol. 2018;35:266-70.

Khaund A, Lumsden M. A benign disease of the uterus. In: Edmonds DK, editor. Dewhurst's textbook of obstetrics and Gynaecology for postgraduates. 8th ed. Oxford: Blackwell Scientific Publication. 2012;715-26.

Ugurlucan FG, Iyibozkurt AC, Sen S, Kuru O, Berkman S. Pyomyoma after dilatation and curettage for missed abortion. Clin Exp Obstet Gynecol. 2013;40:168-9.

Evans AT, Pratt JH. A giant fibroid uterus. Obstet Gynecol. 1979;54:385–6.

Poh TL, Chin HT, Hui LC, Jessie P. Management of a giant uterine leiomyoma: A case report.BJM. 2018;1-4

Machapali S, Morkus EP, Mukherjee TK, Reilly KD. Adominal myomectomy increases fertility outcome. Gynecol Obstet. 2013;3:144.

Verma M, Gupa R, Porwal KS, Gupta S, Swarnkar M. To study the prevalence of pelvic pathology among patients with uterine myoma. J Pharm Biomed Sci. 2013;32:1279-81.

Adelusola KA, Ogunniyi SO. Hysterectomies in Nigerians: Histopathological analysis of cases seen in Ile-Ife. Niger Postgrad Med J. 2001;8:37-40.

Ernest A, Mwakalebela A, Mpondo BC. Uterine leiomyoma in a 19-year-old girl: Case report and literature review. Malawi Medical Journal. 2016;28(1):31-33.

Marshall LM, Spiegelman D, Barbieri RL, Goldman MB, Manson JE, Colditz GA, et al. Variation in the incidence of uterine leiomyoma among premenopausal women by age and race. Obstet Gynecol. 1997;90(6):967-73.

Peddada SD, Laughlin SK, Miner K, Guyon JP, Haneke K, Vahdat HL, et al. Growth of uterine leiomyomata among premenopausal black and white women. Proc Natl Acad Sci U S A.


Antonio Simone Laganà, Daniele Vergara, Alessandro Favilli, Valentina Lucia La Rosa, Andrea Tinelli, Sandro Gerli, Marco Noventa, Amerigo Vitagliano, Onofrio Triolo. Agnese Maria Chiara Rapisarda & Salvatore Giovanni Vitale Archives of Gynecology and Obstetrics. 2017;296(5):855–867.

Panayotidis C, Salleh S, Martin JE, Hirsh P, Wynn J. Giant uterine leiomyomas: dilemmas in surgical management. Gynecol Surg. 2006;3:37–40.

Lethaby AE, Vollenhoven BJ. An evidence-based approach to hormonal therapies for premenopausal women with fibroids. Best Pract Res Clin Obstet Gynaecol. 2008;22(2):307-31.

De Falco M, Pollio F, Pontillo M, Ambrosino E, Busiello A, Carbone IF, et al. GnRH agonists and antagonists in the preoperative therapy of uterine fibroids: literature review. Minerva Ginecol. 2006;56(6)553-60.

Volkers NA, Hehenkamp WJ, Birnie E, de Vries C, Holt C, Ankum WM, et al. Uterine artery embolization in the treatment of symptomatic uterine fibroid tumors (EMMY trial): periprocedural results and complications. J Vasc Interv Radiol. 2006;17(3):471-80.

Goldberg J, Pereira L, Berghella V. Pregnancy after uterine artery embolization. Obstet Gynecol. 2002;100(5 Pt 1):869-72.

Wallach EE, Vlahos NF. Uterine myomas: an overview of development, clinical features, and management. Obstet Gynecol. 2004;104(2):393–406.

Brito LGO, Ueno NL, Machado MR. Does Big Mean Evil? Giant, but benign Uterine Leiomyoma: Case report and review of the literature. Rev Bras Ginecol Obstet. 2021;43(1):66–71.

Oelsner G, Elizur SE, Frenkel Y, Carp H. Giant uterine tumors: two cases with different clinical presentations. Obstet Gynecol. 2003; 101(5 Pt 2):1088–1091

Ezugwu EC, Iyoke CA, Ezugwu FO, Ugwu G. Successful pregnancy following myomectomy for giant uterine fibroid in an infertile woman. J Reprod Infertil. 2014;15(04):233–236.

Abid Rashid, Sultan Ayaz, Riaz ur Rehman, Ejaz Mohiuddin, Muhammad Akram. Fibroid uterus: case report. Pak J Med Biol Sci. 2017;1(2):83-87.