Tiger Nut (Cyperus esculentus L.) Boosts Fertility in Male Wistar Rats
Asian Research Journal of Gynaecology and Obstetrics,
Aim: This study is aimed at investigating the effect of tiger nut on the fertility of male Wistar rats.
Materials and Methods: Twenty-four adult male Wistar rats were divided into four groups of six each. Animals in group A were administered normal saline solution while those in groups B, C and D were administered 1, 2 and 4 mL/kg body weight of undiluted tiger nut milk respectively for twenty-eight days. Administration was done 12 hourly via oral route. At the end of the administration, the rats were sacrificed after an overnight fast under diethyl ether as anesthesia. Blood samples were collected via cardiac puncture. The internal organs were exposed. Testes and cauda epididymis were removed and kept in sterilized watched glass. Sperm quality and sex hormones were determined using standard methods.
Results: Tiger nut milk produced a dose-dependent increase in sperm count and motility of animals treated when compared with those in the control group. The increase in sperm count was only significant (p<0.05) at a dose of 4 mL/kg while that of sperm motility was significant (p<0.05) at doses of 2 and 4 mL/kg body weight. A significant (p<0.05) decrease was observed in the sperm mortality of animals treated with tiger nut milk at all doses while the decrease observed in sperm abnormality was only significant (p<0.05) at a dose of 4 mL/kg when compared with those in the control group. Administration of tiger nut had no significant effect on seminal pH. Administration of tiger nut milk produced a dose-dependent increase in the concentrations of luteinizing hormone (LH) and testosterone of animals treated for 28 days. At a dose of 1 mL/kg, tiger nut milk significantly (p<0.05) decreased the level of follicle stimulating hormone (FSH) of animals when compared with those in control animals while higher doses produced no significant effect.
Conclusion: It is clear from the result of this study that tiger nut possesses boosts fertility in male rats. Thus, men with fertility challenges are encouraged to consider regular consumption of tiger nut.
- Aphrodisiac properties
- sperm quality
- male sex hormone
- tiger nut.
How to Cite
Cooper TG, Noonan E, von Eckardstein S, Auger J, Baker HWG, Behre HM. World Health Organization reference values for human semen characteristics. Human Reproduction. 2010;16:231–245.
Speroff L, Fritz MA. Female infertility, Chapter 27, Clinical Gynecologic Endocrinology and Infertility, Eighth Edition. Lippincott Williams & Wilkins, syf: 2010;11:57.
Sartorius G, Nieschlag E. Paternal age and reproduction. Hum. Reprod. Update. 2010; 16: 65-79.
De Krester DM. Endocrinology of Male Infertility. Brit Med Bullet. 1979;35:187-192.
Amelar RD. Infertility in man. F. A Davis Company, Philadelphia, U.S.A. 1966;30-53.
Jarow JP. Endocrine causes of male infertility. UrolClin North Am. 2003;30:83-90.
Gray EN. Testosterone, Sexual Function, and Cognition. J Clin Endocrinol Metab. 2005;90(7):3838–3846.
Weinbauer GF, Nieschlag E. Gonadotropin control of testicular germ cell development. Adv Exp Med Biol. 1995;317:55-65.
Ali M, Al-Dosary UH, Ahmed M. Refaat, Saranya R. Babu, Abdul Rauf Choudhry. Y-STR Profiling of semen stain evidences of azoospermic individuals. International Journal of Forensic Science & Pathology (IJFP), International Journal of Forensic Science and Pathology. 2015;3(11):210-214.
Jungwirth A, Diemer T, Dohle GR, Giwercman A, Kopa Z, Tournaye H, Krausz C. Guidelines for the investigation and treatment of male infertility. Eur Urol. 2012;61(1):159-163.
Montorsi F, Salonia A, Dehaf, Cestari A, Guazzoni G, Rigatti P, Steef C. Pharmacological management of erectile dysfunction, British Journal of Urology. 2003;8:211-216.
Shabsigh B, Anastasiadics AG. Erectile dysfunction, Annual Review of Medicine. 2003;45:153-168.
Porst H. Phosphodiesterase type-5 inhibitors a critical comparative analysis. EAU update ser. 2004;2:56-63.
Yakubu MT, Bilbis LS, Lawal M, Akanji MA. Effect of repeated administration of sildenafil citrate on selected enzyme activities of liver and kidney of male albino rats. Nigerian Journal of Pure and Applied Sciences. 2003;18:1395-4000.
Mendoza-Lujambio I, Nachtigall LB, Dowsing AT, Chase CD. Infertility in Male; 2008.
Sánchez-Zapata E, Fernández-López J, Pérez-Alvarez AJ. Tiger Nut (Cyperus esculentus) Commercialization: Health aspects, composition, properties, and food applications. Comprehensive Reviews in Food Science and Food Safety. 2012; 11(4):366–377.
Pascual-Seva N, San-Bautista A, Galarza, SL, Maroto JV, Pascual B. Yield and Irrigation Water Use Efficiency for Ridge - and Bed - cultivated Chufa (Cyperus Esculentus L. var. Sativus Boeck). Acta Hort. 2012;936:125-132.
Zhang HY, Hanna MA, Ali Y, Nan L. Yellow nut-sedge tuber oil as a fuel. Industrial Crops and Products. 1996;5(3):177–181.
Airaodion AI, Ogbuagu EO, Ekenjoku JA, Okoroukwu VN, Ogbuagu U, Airaodion EO. Antifertility effect of ethanolic leaf extract of Carica papaya in male Wistar rats. Merit Research Journal of Medicine and Medical Science. 2019;7(10):374-381.
Manafa PO, Mouneke IG, Ekuma-Okereke O, Ebugosi RS, Chukwuma GO, Ibe NC, Chukwuanukwu RC, Ogbuowelu OS, Okocha EC, Nwene KE, Manafa VI, Manafa CC. Levels of testosterone, progesterone and follicle stimulating hormone in male sickle cell subjects in Nnamdi Azikiwe University Teaching Hospital, Nnewi. Acta Scientific Medical Sciences. 2019;3(11):11-20.
Lakhsman J, Changamma C. Antispermatogenic effect of Vernonia amygdalina seed extract on steroidogenesis in albino rats. International Journal of Pharmacy and Pharmaceutical Science. 2013;5(1):25-36.
Hasim BS, Goverdhan NA, Vengaiah V, Changamma C. Impact of Vernonia amygdalina Linn. Seed extraction on some Marker Enzymes in Male Albino Rats. International Journal of Pharmacy and Pharmaceutical Science. 2013;22(2):214-217.
Acott TS, Carr DW. Inhibition of bovine spermatozoa by caudal epididymal fluid: 2 Interaction of pH and acquiescence factor. Biology and Reproduction. 1984;30:926-935.
Ekenjoku JA, Airaodion AI, Okoroukwu VN, Ogbuagu EO, Ogbuagu U. Oral administration of ethanolic extract of Vernonia amygdalina leaves might impact negatively on fertility in male wistar rats. Asian Journal of Medical Principles and Clinical Practice. 2019;2(3):1-8.
Airaodion AI, Ekenjoku JA, Ngwogu KO, Ngwogu AC. Consumption of coconut (Cocosnucifera L.) water improved fertility parameters in male Wistar rats. Asian Journal of Pregnancy and Childbirth. 2019; 2(3):1-7.
Turek PJ, Kim M, Gilbaugh JH, Lipsheetz LI. The clinical characteristics of 82 patients with Sertoli-cell only testis histology. Fertil. Steril. 1995;64:1197-1200.
Reyes-Fuentes A, Chavarria M, Aguila G. Deconvuolution analysis of bioassayable LH secretion and half-life in man with idiopathic oligoasthenspermia. International Journal of Andrology. 1997; 20:188-125.
Oguwike FN, Eluke BC, Eze RI, Asika CM, Nwosu PN, Nwafor C, Onumonu C. The effects of Cyperus esculentus (Tiger nut) on haematological and biochemical profile of male Hypercholesteremic Subjects in Uli, Anambra State Nigeria. Greener Journal of Medical Sciences. 2017;7(4): 036-041.
Airaodion AI, Ekenjoku JA, Ngwogu AC, Ngwogu KO, Megwas AU, Ime AU. Antaphrodisiac potential of bitter kola (Garcinia kola) seeds in male Wistar rats. International Journal of Bio-Science and Bio-Technology. 2020;12(3):36-43.
Fattahi E, Parivar K, Jorsaraei SGA, Moghadamnia AA. The effects of diazinon on testosterone, FSH and LH levels and testicular tissue in mice. Iranian Journal of Reproductive Medicine. 2009;7(2):59-64.
Airaodion AI, Ngwogu AC, Megwas AU,Ekenjoku JA, Ngwogu KO. Effect of common household insecticides used in Nigeria on rat male reproductive hormones. International Journal of Research and Reports in Gynaecology. 2019;2(1):1-8.
Bo C, Zhao W, Jia Q, Yang Z, Sai L, Zhang F, Du Z, Yu G, Xie L, Zhang Z. Effects of α-zearalanol on spermatogenesis and sex hormone levels of male mice. International Journal of Clinical and Experimental Medicine. 2015; 8(11):20002-20013.
Civen M, Brown CB. the effect of organophosphate insecticides on adrenal corticosterone formation. Pesticide Biochemistry and Physiology. 1974;4:254–259.
Allouh MZ, Daradka HM, Ghaida JHA. Influence of Cyperus esculentus tubers (Tiger Nut) on male rat copulatory behavior. BMC Complementary and Alternative Medicine. 2015;15(331):1-7.
Abstract View: 1567 times
PDF Download: 728 times