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Pregnancy in healthy women is associated with normal changes in lipid metabolism that are essential for fetal growth and development. Hyperlipidemia as a cause of pancreatitis as well as severe Hyperlipidemia in pregnancy is not commonly seen in clinical practice. Acute pain abdomen in a pregnant woman near term is almost always related to labour. However, sometimes it could be a presenting feature of some other abdominal pathology. We report a case of acute pancreatitis due to severe Hyperlipidemia in a pregnant woman diagnosed after receiving an alert from the laboratory of highly lipemic serum. The presentation, management and outcome of the case are discussed.